His ability to exploit spaces in transition could prove decisive against a side expected to dominate possession.

Hansi Flick side face an uphill task after the first-leg setback, which was compounded by Pau Cubarsi’s dismissal. However, they arrive in Madrid boosted by a commanding 4-1 victory over Espanyol, a match in which teenage star Lamine Yamal reached 100 La Liga appearances and marked the occasion with a goal and two assists.

The Catalan side currently sit comfortably at the top of La Liga, nine points clear of Real Madrid, but their focus now shifts to overturning the deficit and keeping their European ambitions alive.

While Barcelona have beaten Atletico away from home in recent meetings, memories of a heavy Copa del Rey defeat earlier this year may weigh on their confidence. They must deliver a clinical performance to stand any chance of staging a comeback.

For Lookman, the stage is set to further underline his growing influence in Spanish football, with a place in the Champions League semi-finals within touching distance.